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BMB PhD Program Faculty

Photini Sinnis

Malaria: cell biology & transmission dynamics 

Professor

Department of Molecular Microbiology & Immunology 
Bloomberg School of Public Health

Photini Sinnis

Research Overview

The Sinnis Laboratory studies the sporozoite stage of Plasmodium, the infectious stage of the malaria parasite, inoculated by mosquitoes into the mammalian host. The impressive journey of sporozoites, from the midgut wall of the mosquito where they emerge from oocysts, to their final destination in the mammalian liver, is the major focus of our investigations. Using classic biochemistry, mutational analysis, intravital imaging, and proteomics, we aim to understand the molecular interactions between sporozoites and their mosquito and mammalian hosts that lead to the establishment of malaria infection.

Additional Titles

Associate Professor of Medicine, Division of Infectious Diseases, School of Medicine

Deputy Director, Johns Hopkins Malaria Institute

 

 

Selected Publications