The INnovations to Generate Estimates of children's Soil/dust inTake (INGEST) Study
Infants, toddlers, and young children learn and explore their environment by putting their hands and other objects in their mouths. In order to promote environmental policies that keep this type of exploration safe, scientists need to better understand how much dust and soil children get in their mouths while engaging in these behaviors. Current scientific approaches for figuring out how much soil and dust children get in their mouths do not work well. As a result, we need to develop new ways to estimate their soil and dust exposures.
The INnovations to Generate Estimates of children's Soil/dust inTake (INGEST) Study is a multi-disciplinary effort to improve scientific methods for estimating children’s soil and dust intake. This research has three main objectives:
- To determine how much time children under the age of 6 spend in macro-activities that involve contact with soil and dust, like playing or crawling on the ground: Caregivers of children under 6 years of age will be asked to complete hourly, mobile-based surveys to determine how children spend their time, including sleeping, eating, and playing.
- To develop improved methods to estimate the micro-activities (i.e. hand-to-mouth or object-to-mouth behaviors) of children. We will film children between the ages of 6 and 18 months to record their micro-activities. We will use cutting-edge computer vision and micro-analytic coding to count the number of times these events occur. This will involve teaching computers to count micro-activities, something that is especially labor-intensive without artificial intelligence. We will validate the computer vision method with traditional behavioral coding conducted by people.
- To identify novel organic chemicals that can serve as tracers of children's exposure to soil and dust. We will collect and analyze urine and stool from children between 6 and 12 months and food, soil, and dust from their homes. We will use non-target analysis and analyze the patterns of chemical occurrence in the biological and environmental samples to identify the best possible chemical tracers to use in future studies of soil and dust exposure.
Meet Our Investigators
- Keeve Nachman
- Meghan Davis
- Sara Lupolt
- Carsten Prasse
- Lesliam Quirós-Alcalá
- Kristin Voegtline
- Alan Yuille
- Tracey J. Woodruff
Publications
TITLE | AUTHOR(S) | LINK TO ARTICLE |
---|---|---|
Optimization of a method for collecting infant and toddler urine for non-target analysis using cotton pads and commercially available disposable diapers | Sara N. Lupolt, Matthew N. Newmeyer, Qinfan Lyu, Carsten Prasse, Keeve E. Nachman | https://www.nature.com/articles/s41370-023-00553-x |