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Integrated Multiplexed Serosurveillance in the Countrywide Mortality Surveillance for Action (COMSA) in Mozambique

Challenge

Recent developments in multiplex serological assays provide the tools to establish integrated, multiplexed serosurveillance platforms to measure seroprevalence to vaccine-preventable diseases, enteric pathogens, neglected tropical diseases, and malaria parasites across space, time, and age. The Countrywide Mortality Surveillance for Action (COMSA) surveillance system in Mozambique provides a sampling frame to integrate multiplex serosurveillance and serve as a model for the development of integrated serosurveillance systems elsewhere.

Approach

The overall goal of this project is to demonstrate the feasibility and utility of leveraging the COMSA mortality surveillance platform for integrated, multiplex serosurveillance by generating age-specific seroprevalence estimates to multiple infectious diseases in Zambezia Province.