Departmental Affiliations
Research Interests
RNA viruses, Viral pathogenesis, Viral macrodomain, ADP ribosylation, Neurovirulence
Experiences & Accomplishments
Honors & Awards
2016 Dr M R Das Career Award, Rajiv Gandhi Centre for Biotechnology, Kerala, India
2014 Student Merit Award of the Year, Rajiv Gandhi Centre for Biotechnology, India
2013 Fulbright Nehru Doctoral and Professional Fellowship, Institute of International Education, Washington DC & United States - India Educational Foundation, India
Select Publications
Selected 5 out of 20
1. Rachy Abraham, Debra Hauer, Robert Lyle McPherson, Age Utt, Ilsa Kirby, Michael S. Cohen, Andres Merits, Anthony K. L. Leung, Diane E. Griffin (2018) ADP-ribosyl–binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication. Proceedings of the National Academy of Sciences of the United States of America. 115(44)
2. Robert Lyle McPherson*, Rachy Abraham*, Easwaran Sreekumar*, Shao-En Ong, Shang-Jung Cheng, Victoria K. Baxter, Hans A. V. Kistemaker, Dmitri V. Filippov, Diane E. Griffin, Anthony K. L. Leung (2017) ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence. Proceedings of the National Academy of Sciences of the United States of America. 114(7)1666-1671.
3. Rachy Abraham, Robert L. McPherson, Morgan Dasovich, Mohsen Badjee, Anthony K-L Leung, Diane E. Griffin (2020) Both ADP ribosyl binding and hydrolase activities of the alphavirus nsP3 macrodomain affect neurovirulence in mice. mBio 11(1). doi: 10.1128/mBio.03253-19
4. Taewoo Kim*, Rachy Abraham*, Lisa Pieterse, Jane X.Yeh, Diane E. Griffin (2022) Cell type-dependent role for nsP3 macrodomain ADP-ribose binding and hydrolase activity during chikungunya virus infection. Viruses 14(12):2744 10.3390/v14122744.
5. Sreeja R Nair*, Rachy Abraham*, E. Sreekumar (2022) Generation of a live-attenuated strain of Chikungunya virus from an Indian isolate for vaccine development. Vaccines.10(11), 1939; doi.org/10.3390/vaccines10111939.
(*Equal contribution)https://scholar.google.com/scholar?hl=en&as_sdt=0%2C21&q=rachy+abraham&oq=