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Rachy
Abraham
,
PhD

Assistant Scientist

Contact Info

615 N Wolfe Street, E8209
Baltimore
Maryland
21210
US        

Research Interests

RNA viruses, Viral pathogenesis, Viral macrodomain, ADP ribosylation, Neurovirulence

Experiences & Accomplishments
Education
PhD
University of Kerala
2016
MSc
Mahatma Gandhi University
2008
BSc
University of Kerala
2006
Honors & Awards

2016                Dr M R Das Career Award, Rajiv Gandhi Centre for Biotechnology, Kerala, India 

2014                Student Merit Award of the Year, Rajiv Gandhi Centre for Biotechnology, India 

2013                Fulbright Nehru Doctoral and Professional Fellowship, Institute of International Education, Washington DC & United States - India Educational Foundation, India 

Select Publications

Selected 5 out of 20

  • 1. Rachy Abraham, Debra Hauer, Robert Lyle McPherson, Age Utt, Ilsa Kirby, Michael S. Cohen, Andres Merits, Anthony K. L. Leung, Diane E. Griffin (2018) ADP-ribosyl–binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication. Proceedings of the National Academy of Sciences of the United States of America. 115(44)
    2. Robert Lyle McPherson*, Rachy Abraham*, Easwaran Sreekumar*, Shao-En Ong, Shang-Jung Cheng, Victoria K. Baxter, Hans A. V. Kistemaker, Dmitri V. Filippov, Diane E. Griffin, Anthony K. L. Leung (2017) ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence. Proceedings of the National Academy of Sciences of the United States of America. 114(7)1666-1671. 
    3. Rachy Abraham, Robert L. McPherson, Morgan Dasovich, Mohsen Badjee, Anthony K-L Leung, Diane E. Griffin (2020) Both ADP ribosyl binding and hydrolase activities of the alphavirus nsP3 macrodomain affect neurovirulence in mice. mBio 11(1). doi: 10.1128/mBio.03253-19
    4. Taewoo Kim*, Rachy Abraham*, Lisa Pieterse, Jane X.Yeh, Diane E. Griffin (2022) Cell type-dependent role for nsP3 macrodomain ADP-ribose binding and hydrolase activity during chikungunya virus infection. Viruses 14(12):2744 10.3390/v14122744. 
    5. Sreeja R Nair*, Rachy Abraham*, E. Sreekumar (2022) Generation of a live-attenuated strain of Chikungunya virus from an Indian isolate for vaccine development. Vaccines.10(11), 1939; doi.org/10.3390/vaccines10111939.
    (*Equal contribution)

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