Departmental Affiliations
Center & Institute Affiliations
David Dowdy, MD, PhD ’08, ScM ’02, studies the implementation of interventions to fight tuberculosis, the world's most deadly infectious disease.
Contact Info
Research Interests
infectious diseases; tuberculosis; HIV; epidemiology; mathematical modeling; implementation science; infectious disease dynamics; health economics
Experiences & Accomplishments
I am an infectious disease epidemiologist focused primarily on the epidemiology of tuberculosis (TB). My interdisciplinary research lies at the nexus of experimental and observational epidemiology, infectious disease modeling, health economics, and implementation science.
My primary interests are:
(1) Mechanistic modeling and economic evaluation of TB and TB/HIV: I combine methods from field-based epidemiology, cost-effectiveness analysis, and epidemic modeling with the aim of answering questions of relevance to patients and policy-makers. Many of my research projects focus on the process of case-finding and diagnosis, which remains one of the biggest gaps in TB control efforts worldwide. I am the director of the Bioinformatics, Modeling, and Biostatistics Core (BMBC) of the JHU Tuberculosis Research Advancement Center (JHU TRAC), and I am the PI/MPI of multiple NIH-funded clinical trials of TB case finding (including X-ray images with AI interpretation) and preventive treatment. Much of my work is based in Uganda, as a core faculty member of the Uganda Tuberculosis Implementation Research Consortium (U-TIRC, u-tirc.org) and with the Rakai Health Sciences Program (RHSP, www.rhsp.org) - though I also conduct research in the United States and multiple other countries.
(2) Translational epidemiology: I have great interest in creating modeling frameworks that allow decision-makers to translate epidemiological data into effective decisions. I welcome collaboration from researchers, clinicians, or students having expertise in any field, who hope to create models to translate epidemiological data into meaningful policy, practical, or clinical decisions.
(3) Implementation science: I am interested not only in how interventions operate in idealized settings, but also improving how they are implemented in the real world. I am particularly interested in the cost and cost-effectiveness of improving health systems in LMICs.
(4) Teaching and mentorship: These are essential, and often-undervalued, skills in the field of epidemiology. If our profession is to continue its record of success, I firmly believe that we need to train future leaders how to teach and mentor others, and also to do our best to serve as role models in that regard.
Honors & Awards
Awards since 2008:
2023 Strategic & Technical Advisory Group on Tuberculosis (STAG-TB), World Health Organization
2020 JHU Catalyst Award recipient
2018 Advising, Mentoring, and Teaching Recognition Award (AMTRA), JHSPH
2015 Excellence in Mentoring Award
2014 Golden Apple Teaching Award (large class)
2013 Advising, Mentoring, and Teaching Recognition Award (AMTRA), JHSPH
2012 B. Frank and Kathleen Polk Assistant Professor of Epidemiology
2012 Young Investigator Prize, International Union Against Tuberculosis and Lung Disease
2011 Tom Evans Teaching Award, Internal Medicine Residency Program, UCSF
2010 Diane Becker Award in Clinical Epidemiology and Prevention, Johns Hopkins GIM Housestaff Research Award
2010 Floyd Rector Clinical Science Research Award, Internal Medicine Residency Program, UCSF
2010 Teaching Excellence Award for Cherished Housestaff (TEACH), UCSF School of Medicine
2009 Julius Krevans Award for Outstanding Housestaff Service, San Francisco General Hospital
2008 Warfield T. Longcope Prize in Clinical Medicine, Johns Hopkins University School of Medicine
2008 David E. Rogers Award for Professionalism, Ethics, & Community, Johns Hopkins University School of Medicine
2008 Alpha Omega Alpha Honor Society
2008 Arthur M. Dannenberg, Jr. Award for Tuberculosis Research
Select Publications
Major senior/co-senior author publications in 2025 (all first-authored by primary trainees):
Kendall EA, Dowdy DW. The health impact of identifying a person with tuberculosis through systematic screening. Lancet Infect Dis. 2025 Nov;25(11):e658-e666.
Young N, Biché P, Mohlamonyane M, Morolo M, Maholwana B, Ahmed K, Martinson N, Hanrahan CF, Dowdy DW. Innovative timing strategies for tuberculosis household contact investigation: cost-effectiveness analysis from a randomized trial in rural and urban South Africa (Kharituwe Study). EClinicalMedicine. 2025 May 26;84:103259.
Ryckman TS, Hopkins L, Tang L, Biché P, Mohlamonyane M, Morolo M, Nonyane BAS, Ahmed K, Martinson N, Hanrahan CF, Omar SV, Mathema B, Dowdy DW. Molecular Epidemiology of Mycobacterium tuberculosis Across 3 Distinct Geographic Sites in South Africa. J Infect Dis. 2025 Oct 15;232(4):870-881.
Kendall EA, Denkinger CM, Cattamanchi A, Dowdy DW, Andrews JR. Whom tuberculosis tests detect and why it matters: implications for diagnostic algorithms. Lancet Microbe. 2025 Dec;6(12):101237.
Kasaie P, Dombrowski L, Pennington J, Kenu E, Adusi-Poku Y, Wadie B, Dowdy DW, Schroeder LF. Evaluating the impact of decentralized testing for tuberculosis in Ghana: A simulation model. PLOS Glob Public Health. 2025 Nov 17;5(11):e0005302.