Biostatistics Department Seminar: Hierarchical Bayesian Spatio-Temporal Modeling for Multi-Pathogen Transmission of Hand, Foot, and Mouth Disease
Department & Center Events
Monday, March 25, 2024, 12:05 p.m. - 12:50 p.m. ET
Location
Wolfe Street Building/W2008
Hybrid
Past Event
Biostatistics Department Seminar
Title: Hierarchical Bayesian Spatio-Temporal Modeling for Multi-Pathogen Transmission of Hand, Foot, and Mouth Disease
Abstract: Mathematical modeling of infectious diseases plays an important role in the development and evaluation of intervention plans. These plans, such as the development of vaccines, are usually pathogen-specific, but laboratory confirmation of all pathogen-specific infections is rarely available. If an epidemic is a consequence of co-circulation of several pathogens, it is desirable to jointly model these pathogens in order to study the transmissibility of the disease. Our work is motivated by the hand, foot and mouth disease (HFMD) surveillance data in China. We build a hierarchical Bayesian multi-pathogen model by using a latent process to link the disease counts and the lab test data. Our model explicitly accounts for spatio-temporal disease patterns. The inference is carried out by an MCMC algorithm. We study operating characteristics of the model on simulated data and apply it to the HFMD in China data set.
Speaker
Nikolay Bliznyuk, PhD, is an Associate Professor in the Agricultural And Biological Engineering Department at the University of Florida. His areas of specialization are Bayesian statistics, computational statistics, computer experiments, environmental applications, high-dimensional data, inverse problems, Monte Carlo methods,spatial and spatio-temporal modeling.
Registration
If you would like to join via Zoom, please register here.
2023-2024 Monday Seminar Series
All seminars are held at 12:05 PM via Zoom and onsite in Room W2008. View all seminar information here.