260.711.01
Principles of Neuroimmunology
Location
East Baltimore
Term
4th Term
Department
Molecular Microbiology and Immunology
Credit(s)
3
Academic Year
2024 - 2025
Instruction Method
In-person
Tu, Th, 9:00 - 10:20am
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
Yes
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Contact Name
Frequency Schedule
Every Year
Resources
Prerequisite
Basic knowledge of brain anatomy, physiology and biology.
Briefly covers the role of specific cells of the central nervous system (CNS), immune functions of CNS cells, and trafficking of leukocytes into the CNS, both in health and disease. Subsequently, it discusses various immune cells, e.g. monocytes, T cells, B cells, inflammatory molecules such as cytokines, chemokines, metalloproteinases, and prostaglandins in more detail, focusing on their role in either protecting from neurological disease or in causing CNS disease pathologies, including cognitive dysfunction. Presentations from experts in the field address topics and diseases, such as multiple sclerosis (MS), the blood brain barrier (BBB), HIV and other neurotropic microbes in eliciting neurological disease and emerging neurotropic infections.
Learning Objectives
Upon successfully completing this course, students will be able to:
- Describe the types and effector functions of resident and peripheral immune cells in the human brain, in health and disease
- Explain how the immune system and cellular brain components contribute to neurological disease
Methods of Assessment
This course is evaluated as follows:
- 10% Participation
- 20% Discussion
- 20% Journal club presentation
- 50% Exam(s)
Enrollment Restriction
Basic knowledge of biology