415.866.92
Current Topics in Molecular Genetics I
Location
NIH - Bethesda, MD
Term
3rd Term
Department
Health, Behavior and Society
Credit(s)
1
Academic Year
2024 - 2025
Instruction Method
In-person
Wednesday, 4:00 - 4:50pm
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Course Instructor(s)
Suzanne Hart
Contact Name
Frequency Schedule
Every Year
Resources
Prerequisite
415.610-.613; Must be enrolled in ScM in Genetic Counseling Program
Provides a review of molecular diagnosis of common hereditary or neoplastic disorders for which DNA-based diagnosis is now in routine use, including FGFR3 disorders, fetal blood typing, thrombophilias, hemochromatosis, fragile X syndrome, polyglutamine disorders, hereditary breast cancers, Charcot Marie Tooth and spinal muscular atrophy, Prader Willi and Angelman syndromes, mitochondrial diseases, Duchenne and Becker muscular dystrophy, cystic fibrosis, and Smith-Lemli-Opitz Syndrome. Includes instruction in genetic risk prediction, using linkage and Bayesian analysis as well as DNA forensics and paternity testing.
Learning Objectives
Upon successfully completing this course, students will be able to:
- Describe the types of techniques used in molecular genetic diagnostic laboratories, including the limitations of each assay
- Calculate residual risks after molecular testing
- Discuss how to interpret molecular genetic results
Methods of Assessment
This course is evaluated as follows:
- 50% Participation
- 50% Presentation(s)
Final grade applies to all terms
Students must register for both 3rd and 4th term.